Free Feeding of CpG-Oligodeoxynucleotide Particles Prophylactically Attenuates Allergic Airway Inflammation and Hyperresponsiveness in Mice

CpG-oligodeoxynucleotides (CpG-ODNs) constitute an attractive alternative for asthma treatment. However, very little evidence is available from studies on the oral administration of CpG-ODNs in animals. Previously, we developed acid-resistant particles (named ODNcap) as an oral delivery device for O...

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Bibliographic Details

Main Authors:	Takuma Okajima, Suguru Shigemori, Fu Namai, Tasuku Ogita, Takashi Sato, Takeshi Shimosato
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2021-11-01
Series:	Frontiers in Immunology
Subjects:	CpG-ODNs oral delivery mouse model of allergic asthma airway inflammation airway hyperresponsiveness pulmonary vein cardiomyocytes
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.738041/full
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