Immunoglobulins in Nasal Secretions of Healthy Humans: Structural Integrity of Secretory Immunoglobulin A1 (IgA1) and Occurrence of Neutralizing Antibodies to IgA1 Proteases of Nasal Bacteria

Certain bacteria, including overt pathogens as well as commensals, produce immunoglobulin A1 (IgA1) proteases. By cleaving IgA1, including secretory IgA1, in the hinge region, these enzymes may interfere with the barrier functions of mucosal IgA antibodies, as indicated by experiments in vitro. Prev...

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Detalhes bibliográficos

Publicado no:	Clin Diagn Lab Immunol
Principais autores:	Kirkeby, Line, Rasmussen, Trine Tang, Reinholdt, Jesper, Kilian, Mogens
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Antibodies and Mediators of Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95818/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10618273/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/cdli.7.1.31-39.2000
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