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Immunoglobulins in Nasal Secretions of Healthy Humans: Structural Integrity of Secretory Immunoglobulin A1 (IgA1) and Occurrence of Neutralizing Antibodies to IgA1 Proteases of Nasal Bacteria

Certain bacteria, including overt pathogens as well as commensals, produce immunoglobulin A1 (IgA1) proteases. By cleaving IgA1, including secretory IgA1, in the hinge region, these enzymes may interfere with the barrier functions of mucosal IgA antibodies, as indicated by experiments in vitro. Prev...

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Bibliografiset tiedot
Julkaisussa:Clin Diagn Lab Immunol
Päätekijät: Kirkeby, Line, Rasmussen, Trine Tang, Reinholdt, Jesper, Kilian, Mogens
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95818/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10618273/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/cdli.7.1.31-39.2000
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