Immunoglobulins in Nasal Secretions of Healthy Humans: Structural Integrity of Secretory Immunoglobulin A1 (IgA1) and Occurrence of Neutralizing Antibodies to IgA1 Proteases of Nasal Bacteria

Certain bacteria, including overt pathogens as well as commensals, produce immunoglobulin A1 (IgA1) proteases. By cleaving IgA1, including secretory IgA1, in the hinge region, these enzymes may interfere with the barrier functions of mucosal IgA antibodies, as indicated by experiments in vitro. Prev...

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Vydáno v:	Clin Diagn Lab Immunol
Hlavní autoři:	Kirkeby, Line, Rasmussen, Trine Tang, Reinholdt, Jesper, Kilian, Mogens
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2000
Témata:	Antibodies and Mediators of Immunity
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95818/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10618273/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/cdli.7.1.31-39.2000
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