Immunoglobulins in Nasal Secretions of Healthy Humans: Structural Integrity of Secretory Immunoglobulin A1 (IgA1) and Occurrence of Neutralizing Antibodies to IgA1 Proteases of Nasal Bacteria

Certain bacteria, including overt pathogens as well as commensals, produce immunoglobulin A1 (IgA1) proteases. By cleaving IgA1, including secretory IgA1, in the hinge region, these enzymes may interfere with the barrier functions of mucosal IgA antibodies, as indicated by experiments in vitro. Prev...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Kirkeby, Line, Rasmussen, Trine Tang, Reinholdt, Jesper, Kilian, Mogens
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2000
الموضوعات:
Antibodies and Mediators of Immunity
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC95818/
https://ncbi.nlm.nih.gov/pubmed/10618273
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