Antibiotic Activity and Characterization of BB-3497, a Novel Peptide Deformylase Inhibitor

Peptide deformylase (PDF) is an essential bacterial metalloenzyme which deformylates the N-formylmethionine of newly synthesized polypeptides and as such represents a novel target for antibacterial chemotherapy. To identify novel PDF inhibitors, we screened a metalloenzyme inhibitor library and iden...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Antimicrob Agents Chemother
Päätekijät:	Clements, John M., Beckett, R. Paul, Brown, Anthony, Catlin, Graham, Lobell, Mario, Palan, Shilpa, Thomas, Wayne, Whittaker, Mark, Wood, Stephen, Salama, Sameeh, Baker, Patrick J., Rodgers, H. Fiona, Barynin, Vladimir, Rice, David W., Hunter, Michael G.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 2001
Aiheet:	Experimental Therapeutics
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90327/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158755/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.2.563-570.2001
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