Efficacy of BAL5788, a Prodrug of Cephalosporin BAL9141, in a Mouse Model of Acute Pneumococcal Pneumonia

BAL5788 is a water-soluble prodrug of BAL9141, a new broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- and vancomycin-resistant staphylococci and penicillin-resistant streptococci. In plasma BAL5788 is rapidly converted to BAL9141. We studied the activity of BAL...

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Hlavní autoři: Azoulay-Dupuis, E., Bédos, J. P., Mohler, J., Schmitt-Hoffmann, A., Schleimer, M., Shapiro, S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC375270/
https://ncbi.nlm.nih.gov/pubmed/15047508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1105-1111.2004
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