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Efficacy of BAL5788, a Prodrug of Cephalosporin BAL9141, in a Mouse Model of Acute Pneumococcal Pneumonia

BAL5788 is a water-soluble prodrug of BAL9141, a new broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- and vancomycin-resistant staphylococci and penicillin-resistant streptococci. In plasma BAL5788 is rapidly converted to BAL9141. We studied the activity of BAL...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Azoulay-Dupuis, E., Bédos, J. P., Mohler, J., Schmitt-Hoffmann, A., Schleimer, M., Shapiro, S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC375270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15047508/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.4.1105-1111.2004
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