Stimulation of Homologous Recombination through Targeted Cleavage by Chimeric Nucleases

Chimeric nucleases that are hybrids between a nonspecific DNA cleavage domain and a zinc finger DNA recognition domain were tested for their ability to find and cleave their target sites in living cells. Both engineered DNA substrates and the nucleases were injected into Xenopus laevis oocyte nuclei...

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Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Bibikova, Marina, Carroll, Dana, Segal, David J., Trautman, Jonathan K., Smith, Jeff, Kim, Yang-Gyun, Chandrasegaran, Srinivasan
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 2001
Предметы:	DNA Dynamics and Chromosome Structure
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC88802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11113203/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.1.289-297.2001
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