Stimulation of Homologous Recombination through Targeted Cleavage by Chimeric Nucleases

Chimeric nucleases that are hybrids between a nonspecific DNA cleavage domain and a zinc finger DNA recognition domain were tested for their ability to find and cleave their target sites in living cells. Both engineered DNA substrates and the nucleases were injected into Xenopus laevis oocyte nuclei...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bibikova, Marina, Carroll, Dana, Segal, David J., Trautman, Jonathan K., Smith, Jeff, Kim, Yang-Gyun, Chandrasegaran, Srinivasan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2001
विषय:
DNA Dynamics and Chromosome Structure
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC88802/
https://ncbi.nlm.nih.gov/pubmed/11113203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.1.289-297.2001
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