A detailed study of the substrate specificity of a chimeric restriction enzyme.

Recently, the crystal structure of the designed zinc finger protein, DeltaQNK, bound to a preferred DNA sequence was reported. We have converted DeltaQNK into a novel site-specific endonuclease by linking it to the Fok I cleavage domain (FN). The substrate specificity and DNA cleavage properties of...

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Detaylı Bibliyografya
Asıl Yazarlar: Smith, J, Berg, J M, Chandrasegaran, S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1999
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC148231/
https://ncbi.nlm.nih.gov/pubmed/9862996
Etiketler: Etiketle
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