A detailed study of the substrate specificity of a chimeric restriction enzyme.

Recently, the crystal structure of the designed zinc finger protein, DeltaQNK, bound to a preferred DNA sequence was reported. We have converted DeltaQNK into a novel site-specific endonuclease by linking it to the Fok I cleavage domain (FN). The substrate specificity and DNA cleavage properties of...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Nucleic Acids Res
Päätekijät:	Smith, J, Berg, J M, Chandrasegaran, S
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Oxford University Press 1999
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148231/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9862996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.2.674
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!