Stimulation of Homologous Recombination through Targeted Cleavage by Chimeric Nucleases

Chimeric nucleases that are hybrids between a nonspecific DNA cleavage domain and a zinc finger DNA recognition domain were tested for their ability to find and cleave their target sites in living cells. Both engineered DNA substrates and the nucleases were injected into Xenopus laevis oocyte nuclei...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Mol Cell Biol
Prif Awduron:	Bibikova, Marina, Carroll, Dana, Segal, David J., Trautman, Jonathan K., Smith, Jeff, Kim, Yang-Gyun, Chandrasegaran, Srinivasan
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Taylor & Francis 2001
Pynciau:	DNA Dynamics and Chromosome Structure
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC88802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11113203/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.1.289-297.2001
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