The Elongation Domain of ELL Is Dispensable but Its ELL-Associated Factor 1 Interaction Domain Is Essential for MLL-ELL-Induced Leukemogenesis

The MLL-ELL chimeric gene is the product of the (11;19)(q23p13.1) translocation associated with de novo and therapy-related acute myeloid leukemias (AML). ELL is an RNA polymerase II elongation factor that interacts with the recently identified EAF1 (ELL associated factor 1) protein. EAF1 contains a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Luo, Roger T., Lavau, Catherine, Du, Changchun, Simone, Federico, Polak, Paul E., Kawamata, Shin, Thirman, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC87288/
https://ncbi.nlm.nih.gov/pubmed/11463848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5678-5687.2001
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker