טוען...
The Elongation Domain of ELL Is Dispensable but Its ELL-Associated Factor 1 Interaction Domain Is Essential for MLL-ELL-Induced Leukemogenesis
The MLL-ELL chimeric gene is the product of the (11;19)(q23p13.1) translocation associated with de novo and therapy-related acute myeloid leukemias (AML). ELL is an RNA polymerase II elongation factor that interacts with the recently identified EAF1 (ELL associated factor 1) protein. EAF1 contains a...
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| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology
2001
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87288/ https://ncbi.nlm.nih.gov/pubmed/11463848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5678-5687.2001 |
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