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Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia

As a result of the recurring translocation t(11;16) (q23;p13.3), MLL (mixed-lineage leukemia) is fused in frame to CBP (CREB binding protein). This translocation has been documented almost exclusively in cases of acute leukemia or myelodysplasia secondary to therapy with drugs that target DNA topo i...

詳細記述

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書誌詳細
主要な著者: Lavau, Catherine, Du, Changchun, Thirman, Michael, Zeleznik-Le, Nancy
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC302066/
https://ncbi.nlm.nih.gov/pubmed/10970858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.17.4655
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