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ELL and EAF1 are Cajal Body Components That Are Disrupted in MLL-ELL Leukemia
The (11;19)(q23;p13.1) translocation in acute leukemia results in the formation of a chimeric MLL-ELL fusion protein. ELL is an RNA Polymerase II (Pol II) transcriptional elongation factor that interacts with the recently identified EAF1 protein. Here, we show that ELL and EAF1 are components of Caj...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Cell Biology
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153119/ https://ncbi.nlm.nih.gov/pubmed/12686606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-07-0394 |
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