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ELL and EAF1 are Cajal Body Components That Are Disrupted in MLL-ELL Leukemia

The (11;19)(q23;p13.1) translocation in acute leukemia results in the formation of a chimeric MLL-ELL fusion protein. ELL is an RNA Polymerase II (Pol II) transcriptional elongation factor that interacts with the recently identified EAF1 protein. Here, we show that ELL and EAF1 are components of Caj...

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Bibliografische gegevens
Hoofdauteurs: Polak, Paul E., Simone, Federico, Kaberlein, Joseph J., Luo, Roger T., Thirman, Michael J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC153119/
https://ncbi.nlm.nih.gov/pubmed/12686606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-07-0394
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