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A Novel Positive Feedback Loop Mediated by the Docking Protein Gab1 and Phosphatidylinositol 3-Kinase in Epidermal Growth Factor Receptor Signaling

The Gab1 protein is tyrosine phosphorylated in response to various growth factors and serves as a docking protein that recruits a number of downstream signaling proteins, including phosphatidylinositol 3-kinase (PI-3 kinase). To determine the role of Gab1 in signaling via the epidermal growth factor...

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Main Authors: Rodrigues, Gerard A., Falasca, Marco, Zhang, Zhongtao, Ong, Siew Hwa, Schlessinger, Joseph
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2000
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC85307/
https://ncbi.nlm.nih.gov/pubmed/10648629
תגים: הוספת תג
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