The Docking Protein Gab1 Is an Essential Component of an Indirect Mechanism for Fibroblast Growth Factor Stimulation of the Phosphatidylinositol 3-Kinase/Akt Antiapoptotic Pathway

The docking protein Gab1 has been implicated as a mediator of multiple signaling pathways that are activated by a variety of receptor tyrosine kinases and cytokines. We have previously proposed that fibroblast growth factor 1 (FGF1) stimulation of tyrosine phosphorylation of Gab1 and recruitment of...

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Hlavní autoři: Lamothe, Betty, Yamada, Masashi, Schaeper, Ute, Birchmeier, Walter, Lax, Irit, Schlessinger, Joseph
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC480891/
https://ncbi.nlm.nih.gov/pubmed/15199124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.5657-5666.2004
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