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FRS2α attenuates FGF receptor signaling by Grb2- mediated recruitment of the ubiquitin ligase Cbl

Attenuation of growth factor signaling is essential for the regulation of developmental processes and tissue homeostasis in most organisms. The product of Cbl protooncogene is one such regulator, which functions as an ubiquitin ligase that ubiquitinates and promotes the degradation of a variety of c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wong, Andy, Lamothe, Betty, Lee, Arnold, Schlessinger, Joseph, Lax, Irit
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC124463/
https://ncbi.nlm.nih.gov/pubmed/11997436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052138899
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