FRS2α attenuates FGF receptor signaling by Grb2- mediated recruitment of the ubiquitin ligase Cbl

Attenuation of growth factor signaling is essential for the regulation of developmental processes and tissue homeostasis in most organisms. The product of Cbl protooncogene is one such regulator, which functions as an ubiquitin ligase that ubiquitinates and promotes the degradation of a variety of c...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wong, Andy, Lamothe, Betty, Lee, Arnold, Schlessinger, Joseph, Lax, Irit
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124463/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11997436/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052138899
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