Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins

The docking protein FRS2 is a major downstream effector that links fibroblast growth factor (FGF) and nerve growth factor receptors with the Ras/mitogen-activated protein kinase signaling cascade. In this report, we demonstrate that FRS2 also plays a pivotal role in FGF-induced recruitment and activ...

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发表在:	Proc Natl Acad Sci U S A
Principais autores:	Ong, S. H., Hadari, Y. R., Gotoh, N., Guy, G. R., Schlessinger, J., Lax, I.
格式:	Artigo
语言:	Inglês
出版:	National Academy of Sciences 2001
主题:	Biological Sciences
在线阅读:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33424/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11353842/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.111114298
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