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Docking Protein FRS2 Links the Protein Tyrosine Kinase RET and Its Oncogenic Forms with the Mitogen-Activated Protein Kinase Signaling Cascade
The receptor tyrosine kinase RET functions as the signal transducing receptor for the GDNF (for “glial cell-derived neurotrophic factors”) family of ligands. Mutations in the RET gene were implicated in Hirschsprung disease (HSCR), multiple endocrine neoplasia type 2 (MEN 2), and thyroid carcinomas....
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology
2001
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87079/ https://ncbi.nlm.nih.gov/pubmed/11390647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.13.4177-4187.2001 |
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