Docking Protein FRS2 Links the Protein Tyrosine Kinase RET and Its Oncogenic Forms with the Mitogen-Activated Protein Kinase Signaling Cascade

The receptor tyrosine kinase RET functions as the signal transducing receptor for the GDNF (for “glial cell-derived neurotrophic factors”) family of ligands. Mutations in the RET gene were implicated in Hirschsprung disease (HSCR), multiple endocrine neoplasia type 2 (MEN 2), and thyroid carcinomas....

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Main Authors: Melillo, R. M., Santoro, M., Ong, S.-H., Billaud, M., Fusco, A., Hadari, Y. R., Schlessinger, J., Lax, I.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC87079/
https://ncbi.nlm.nih.gov/pubmed/11390647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.13.4177-4187.2001
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