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The G(2) Checkpoint Is Maintained by Redundant Pathways

While p53 activity is critical for a DNA damage-induced G(1) checkpoint, its role in the G(2) checkpoint has not been compelling because cells lacking p53 retain the ability to arrest in G(2) following DNA damage. Comparison between normal human foreskin fibroblasts (HFFs) and HFFs in which p53 was...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Passalaris, Tina M., Benanti, Jennifer A., Gewin, Lindy, Kiyono, Tohru, Galloway, Denise A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84436/
https://ncbi.nlm.nih.gov/pubmed/10454534
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