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The G(2) Checkpoint Is Maintained by Redundant Pathways

While p53 activity is critical for a DNA damage-induced G(1) checkpoint, its role in the G(2) checkpoint has not been compelling because cells lacking p53 retain the ability to arrest in G(2) following DNA damage. Comparison between normal human foreskin fibroblasts (HFFs) and HFFs in which p53 was...

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Bibliografske podrobnosti
Main Authors: Passalaris, Tina M., Benanti, Jennifer A., Gewin, Lindy, Kiyono, Tohru, Galloway, Denise A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC84436/
https://ncbi.nlm.nih.gov/pubmed/10454534
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