Kratom Alkaloids as Probes for Opioid Receptor Function: Pharmacological Characterization of Minor Indole and Oxindole Alkaloids from Kratom

Dry leaves of kratom (mitragyna speciosa) are anecdotally consumed as pain relievers and antidotes against opioid withdrawal and alcohol use disorders. There are at least 54 alkaloids in kratom; however, investigations to date have focused around mitragynine, 7-hydroxy mitragynine (7OH), and mitragy...

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Vydáno v:ACS Chem Neurosci
Hlavní autoři: Chakraborty, Soumen, Uprety, Rajendra, Daibani, Amal E., Rouzic, Valerie L., Hunkele, Amanda, Appourchaux, Kevin, Eans, Shainnel O., Nuthikattu, Nitin, Jilakara, Rahul, Thammavong, Lisa, Pasternak, Gavril W., Pan, Ying-Xian, McLaughlin, Jay P., Che, Tao, Majumdar, Susruta
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8328003/
https://ncbi.nlm.nih.gov/pubmed/34213886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.1c00149
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