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G protein‐biased kratom‐alkaloids and synthetic carfentanil‐amide opioids as potential treatments for alcohol use disorder

BACKGROUND AND PURPOSE: Mitragyna speciosa, more commonly known as kratom, is a plant that contains opioidergic alkaloids but is unregulated in most countries. Kratom is used in the self‐medication of chronic pain and to reduce illicit and prescription opioid dependence. Kratom may be less dangerous...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Gutridge, Anna M., Robins, Meridith T., Cassell, Robert J., Uprety, Rajendra, Mores, Kendall L., Ko, Mee Jung, Pasternak, Gavril W., Majumdar, Susruta, van Rijn, Richard M.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060366/
https://ncbi.nlm.nih.gov/pubmed/31705528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14913
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