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G protein‐biased kratom‐alkaloids and synthetic carfentanil‐amide opioids as potential treatments for alcohol use disorder

BACKGROUND AND PURPOSE: Mitragyna speciosa, more commonly known as kratom, is a plant that contains opioidergic alkaloids but is unregulated in most countries. Kratom is used in the self‐medication of chronic pain and to reduce illicit and prescription opioid dependence. Kratom may be less dangerous...

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Détails bibliographiques
Publié dans:Br J Pharmacol
Auteurs principaux: Gutridge, Anna M., Robins, Meridith T., Cassell, Robert J., Uprety, Rajendra, Mores, Kendall L., Ko, Mee Jung, Pasternak, Gavril W., Majumdar, Susruta, van Rijn, Richard M.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060366/
https://ncbi.nlm.nih.gov/pubmed/31705528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14913
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