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Kratom alkaloids, natural and semi-synthetic, show less physical dependence and ameliorate opioid withdrawal
Chronic administration of opioids produces physical dependence and opioid-induced hyperalgesia. Users claim the Thai traditional tea “Kratom” and component alkaloid mitragynine ameliorate opioid withdrawal without increased sensitivity to pain. Testing these claims, we assessed the combined Kratom a...
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| Pubblicato in: | Cell Mol Neurobiol |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8164968/ https://ncbi.nlm.nih.gov/pubmed/33433723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-020-01034-7 |
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