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Synthesis of Carfentanil Amide Opioids Using the Ugi Multicomponent Reaction
[Image: see text] We report a novel approach to synthesize carfentanil amide analogues utilizing the isocyanide-based four-component Ugi multicomponent reaction. A small library of bis-amide analogues of carfentanil was created using N-alkylpiperidones, aniline, propionic acid, and various aliphatic...
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| 發表在: | ACS Chem Neurosci |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4641535/ https://ncbi.nlm.nih.gov/pubmed/26148793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00137 |
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