A piggyBac-based platform for genome editing and clonal rhesus macaque iPSC line derivation

Non-human primates (NHPs) are, due to their close phylogenetic relationship to humans, excellent animal models to study clinically relevant mutations. However, the toolbox for the genetic modification of NHPs is less developed than those for other species like mice. Therefore, it is necessary to fur...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Rodriguez-Polo, Ignacio, Mißbach, Sophie, Petkov, Stoyan, Mattern, Felix, Maierhofer, Anna, Grządzielewska, Iga, Tereshchenko, Yuliia, Urrutia-Cabrera, Daniel, Haaf, Thomas, Dressel, Ralf, Bartels, Iris, Behr, Rüdiger
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322147/
https://ncbi.nlm.nih.gov/pubmed/34326359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94419-7
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