A piggyBac-based platform for genome editing and clonal rhesus macaque iPSC line derivation

Non-human primates (NHPs) are, due to their close phylogenetic relationship to humans, excellent animal models to study clinically relevant mutations. However, the toolbox for the genetic modification of NHPs is less developed than those for other species like mice. Therefore, it is necessary to fur...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Rodriguez-Polo, Ignacio, Mißbach, Sophie, Petkov, Stoyan, Mattern, Felix, Maierhofer, Anna, Grządzielewska, Iga, Tereshchenko, Yuliia, Urrutia-Cabrera, Daniel, Haaf, Thomas, Dressel, Ralf, Bartels, Iris, Behr, Rüdiger
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322147/
https://ncbi.nlm.nih.gov/pubmed/34326359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94419-7
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