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A piggyBac-based platform for genome editing and clonal rhesus macaque iPSC line derivation

Non-human primates (NHPs) are, due to their close phylogenetic relationship to humans, excellent animal models to study clinically relevant mutations. However, the toolbox for the genetic modification of NHPs is less developed than those for other species like mice. Therefore, it is necessary to fur...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Rodriguez-Polo, Ignacio, Mißbach, Sophie, Petkov, Stoyan, Mattern, Felix, Maierhofer, Anna, Grządzielewska, Iga, Tereshchenko, Yuliia, Urrutia-Cabrera, Daniel, Haaf, Thomas, Dressel, Ralf, Bartels, Iris, Behr, Rüdiger
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322147/
https://ncbi.nlm.nih.gov/pubmed/34326359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94419-7
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