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A piggyBac-based platform for genome editing and clonal rhesus macaque iPSC line derivation

Non-human primates (NHPs) are, due to their close phylogenetic relationship to humans, excellent animal models to study clinically relevant mutations. However, the toolbox for the genetic modification of NHPs is less developed than those for other species like mice. Therefore, it is necessary to fur...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Rodriguez-Polo, Ignacio, Mißbach, Sophie, Petkov, Stoyan, Mattern, Felix, Maierhofer, Anna, Grządzielewska, Iga, Tereshchenko, Yuliia, Urrutia-Cabrera, Daniel, Haaf, Thomas, Dressel, Ralf, Bartels, Iris, Behr, Rüdiger
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322147/
https://ncbi.nlm.nih.gov/pubmed/34326359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94419-7
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