Local Mutations Can Serve as a Game Changer for Global Protein Solvent Interaction

[Image: see text] Although it is well-known that limited local mutations of enzymes, such as matrix metalloproteinases (MMPs), may change enzyme activity by orders of magnitude as well as its stability, the completely rational design of proteins is still challenging. These local changes alter the el...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:JACS Au
Päätekijät: Adams, Ellen M., Pezzotti, Simone, Ahlers, Jonas, Rüttermann, Maximilian, Levin, Maxim, Goldenzweig, Adi, Peleg, Yoav, Fleishman, Sarel J., Sagi, Irit, Havenith, Martina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2021
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317155/
https://ncbi.nlm.nih.gov/pubmed/34337607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacsau.1c00155
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia