Local Mutations Can Serve as a Game Changer for Global Protein Solvent Interaction

[Image: see text] Although it is well-known that limited local mutations of enzymes, such as matrix metalloproteinases (MMPs), may change enzyme activity by orders of magnitude as well as its stability, the completely rational design of proteins is still challenging. These local changes alter the el...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:JACS Au
Autors principals: Adams, Ellen M., Pezzotti, Simone, Ahlers, Jonas, Rüttermann, Maximilian, Levin, Maxim, Goldenzweig, Adi, Peleg, Yoav, Fleishman, Sarel J., Sagi, Irit, Havenith, Martina
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2021
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317155/
https://ncbi.nlm.nih.gov/pubmed/34337607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacsau.1c00155
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars