STING suppresses bone cancer pain via immune and neuronal modulation

Patients with advanced stage cancers frequently suffer from severe pain as a result of bone metastasis and bone destruction, for which there is no efficacious treatment. Here, using multiple mouse models of bone cancer, we report that agonists of the immune regulator STING (stimulator of interferon...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Wang, Kaiyuan, Donnelly, Christopher R., Jiang, Changyu, Liao, Yihan, Luo, Xin, Tao, Xueshu, Bang, Sangsu, McGinnis, Aidan, Lee, Michael, Hilton, Matthew J., Ji, Ru-Rong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316360/
https://ncbi.nlm.nih.gov/pubmed/34315904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24867-2
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