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STING suppresses bone cancer pain via immune and neuronal modulation

Patients with advanced stage cancers frequently suffer from severe pain as a result of bone metastasis and bone destruction, for which there is no efficacious treatment. Here, using multiple mouse models of bone cancer, we report that agonists of the immune regulator STING (stimulator of interferon...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Wang, Kaiyuan, Donnelly, Christopher R., Jiang, Changyu, Liao, Yihan, Luo, Xin, Tao, Xueshu, Bang, Sangsu, McGinnis, Aidan, Lee, Michael, Hilton, Matthew J., Ji, Ru-Rong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316360/
https://ncbi.nlm.nih.gov/pubmed/34315904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24867-2
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