STING controls nociception via type-I interferon signaling in sensory neurons

The innate immune regulator STING is a critical sensor of self- and pathogen-derived DNA, leading to the induction of type-I interferons (IFN-I) and other cytokines which promote immune cell-mediated eradication of pathogens and neoplastic cells (1,2). STING has also emerged as a robust driver of an...

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Gepubliceerd in:Nature
Hoofdauteurs: Donnelly, Christopher R., Jiang, Changyu, Andriessen, Amanda S., Wang, Kaiyuan, Wang, Zilong, Ding, Huiping, Zhao, Junli, Luo, Xin, Lee, Michael S., Lei, Yu L., Maixner, William, Ko, Mei-Chuan, Ji, Ru-Rong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7977781/
https://ncbi.nlm.nih.gov/pubmed/33442058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-03151-1
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