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Anti-PD-1 treatment impairs opioid antinociception in rodents and nonhuman primates
Emerging immunotherapies with monoclonal antibodies against programmed cell death protein-1 (PD-1) have shown success in treating cancers. However, PD-1 signaling in neurons is largely unknown. We recently reported that dorsal root ganglion (DRG) primary sensory neurons express PD-1 and activation o...
Shranjeno v:
| izdano v: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7536651/ https://ncbi.nlm.nih.gov/pubmed/32075945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaw6471 |
| Oznake: |
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