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PD-1 blockade inhibits osteoclast formation and murine bone cancer pain
Emerging immune therapy, such as with the anti–programmed cell death–1 (anti–PD-1) monoclonal antibody nivolumab, has shown efficacy in tumor suppression. Patients with terminal cancer suffer from cancer pain as a result of bone metastasis and bone destruction, but how PD-1 blockade affects bone can...
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| Gepubliceerd in: | J Clin Invest |
|---|---|
| Hoofdauteurs: | , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Clinical Investigation
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7324182/ https://ncbi.nlm.nih.gov/pubmed/32484460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133334 |
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