Cooperation of Oncolytic Herpes Virotherapy and PD-1 Blockade in Murine Rhabdomyosarcoma Models

Oncolytic virotherapy is an effective immunotherapeutic approach for cancer treatment via a multistep process including direct tumor cell lysis, induction of cytotoxic or apoptosis-sensitizing cytokines and promotion of antitumor T cell responses. Solid tumors limit the effectiveness of immunotherap...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Chun-Yu, Wang, Pin-Yi, Hutzen, Brian, Sprague, Les, Swain, Hayley M., Love, Julia K., Stanek, Joseph R., Boon, Louis, Conner, Joe, Cripe, Timothy P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443787/
https://ncbi.nlm.nih.gov/pubmed/28539588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02503-8
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