Neuroblastomas Vary Widely in Their Sensitivities to Herpes Simplex Virotherapy Unrelated to Virus Receptors and Susceptibility

Although most high-risk neuroblastomas are responsive to chemotherapy, relapse is common and long-term survival is less than 40%, underscoring the need for more effective treatments. We evaluated the responsiveness of 12 neuroblastoma cell lines to the Δγ(1)34.5 attenuated oncolytic HSV, Seprehvir (...

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Veröffentlicht in:Gene Ther
Hauptverfasser: Wang, Pin-Yi, Swain, Hayley M., Kunkler, Anne L., Chen, Chun-Yu, Hutzen, Brian J., Arnold, Michael A., Streby, Keri A., Collins, Margaret H., Dipasquale, Betsy, Stanek, Joseph R., Conner, Joe, van Kuppevelt, Toin H., Glorioso, Joseph C., Grandi, Paola, Cripe, Timothy P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742391/
https://ncbi.nlm.nih.gov/pubmed/26583803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2015.105
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