Neuroblastomas Vary Widely in Their Sensitivities to Herpes Simplex Virotherapy Unrelated to Virus Receptors and Susceptibility

Although most high-risk neuroblastomas are responsive to chemotherapy, relapse is common and long-term survival is less than 40%, underscoring the need for more effective treatments. We evaluated the responsiveness of 12 neuroblastoma cell lines to the Δγ(1)34.5 attenuated oncolytic HSV, Seprehvir (...

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Detalhes bibliográficos
Publicado no:Gene Ther
Main Authors: Wang, Pin-Yi, Swain, Hayley M., Kunkler, Anne L., Chen, Chun-Yu, Hutzen, Brian J., Arnold, Michael A., Streby, Keri A., Collins, Margaret H., Dipasquale, Betsy, Stanek, Joseph R., Conner, Joe, van Kuppevelt, Toin H., Glorioso, Joseph C., Grandi, Paola, Cripe, Timothy P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742391/
https://ncbi.nlm.nih.gov/pubmed/26583803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2015.105
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