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Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics
Macrolides and ketolides comprise a family of clinically important antibiotics that inhibit protein synthesis by binding within the exit tunnel of the bacterial ribosome. While these antibiotics are known to interrupt translation at specific sequence motifs, with ketolides predominantly stalling at...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8298421/ https://ncbi.nlm.nih.gov/pubmed/34294725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24674-9 |
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