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How macrolide antibiotics work

Macrolide antibiotics inhibit protein synthesis by targeting the bacterial ribosome. They bind at the nascent peptide exit tunnel and partially occlude it. Thus, macrolides have been viewed as ‘tunnel plugs’ that stop synthesis of every protein. More recent evidence, however, demonstrates that macro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Trends Biochem Sci
Egile Nagusiak: Vázquez-Laslop, Nora, Mankin, Alexander S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108949/
https://ncbi.nlm.nih.gov/pubmed/30054232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.06.011
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