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How macrolide antibiotics work
Macrolide antibiotics inhibit protein synthesis by targeting the bacterial ribosome. They bind at the nascent peptide exit tunnel and partially occlude it. Thus, macrolides have been viewed as ‘tunnel plugs’ that stop synthesis of every protein. More recent evidence, however, demonstrates that macro...
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| Publicado no: | Trends Biochem Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6108949/ https://ncbi.nlm.nih.gov/pubmed/30054232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.06.011 |
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