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Context-specific action of macrolide antibiotics on the eukaryotic ribosome
Macrolide antibiotics bind in the nascent peptide exit tunnel of the bacterial ribosome and prevent polymerization of specific amino acid sequences, selectively inhibiting translation of a subset of proteins. Because preventing translation of individual proteins could be beneficial for the treatment...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8121947/ https://ncbi.nlm.nih.gov/pubmed/33990576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23068-1 |
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