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Context-specific action of macrolide antibiotics on the eukaryotic ribosome

Macrolide antibiotics bind in the nascent peptide exit tunnel of the bacterial ribosome and prevent polymerization of specific amino acid sequences, selectively inhibiting translation of a subset of proteins. Because preventing translation of individual proteins could be beneficial for the treatment...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Svetlov, Maxim S., Koller, Timm O., Meydan, Sezen, Shankar, Vaishnavi, Klepacki, Dorota, Polacek, Norbert, Guydosh, Nicholas R., Vázquez-Laslop, Nora, Wilson, Daniel N., Mankin, Alexander S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121947/
https://ncbi.nlm.nih.gov/pubmed/33990576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23068-1
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