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Kidney-specific Klotho Gene Deletion Causes Aortic Aneurysm via Hyperphosphatemia
Klotho is an aging-suppressor gene. The purpose of this study was to determine whether deletion of the klotho gene in kidneys causes aortic aneurysm (AA) and investigate the underlying mechanisms. Klotho-floxed alleles and tamoxifen-inducible kidney specific CreER(T2) mice were crossed to generate K...
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| Publicado no: | Hypertension |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8285030/ https://ncbi.nlm.nih.gov/pubmed/34176284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.121.17299 |
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