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Secreted Klotho Attenuated Inflammation-Associated Aortic Valve Fibrosis in Senescence Accelerated Mice P1 (SAMP1)
Senescence accelerated mice P1 (SAMP1) is an aging model characterized by shortened lifespan and early signs of senescence. Klotho is an aging-suppressor gene. The purpose of this study is to investigate whether in vivo expression of secreted klotho (Skl) gene attenuates aortic valve fibrosis in SAM...
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| Veröffentlicht in: | Hypertension |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5897144/ https://ncbi.nlm.nih.gov/pubmed/29581213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10560 |
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