Evogliptin Suppresses Calcific Aortic Valve Disease by Attenuating Inflammation, Fibrosis, and Calcification

Calcific aortic valve disease (CAVD) accompanies inflammatory cell infiltration, fibrosis, and ultimately calcification of the valve leaflets. We previously demonstrated that dipeptidyl peptidase-4 (DPP-4) is responsible for the progression of aortic valvular calcification in CAVD animal models. As...

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Pubblicato in:Cells
Autori principali: Choi, Bongkun, Kim, Eun-Young, Kim, Ji-Eun, Oh, Soyoon, Park, Si-On, Kim, Sang-Min, Choi, Hyuksu, Song, Jae-Kwan, Chang, Eun-Ju
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824080/
https://ncbi.nlm.nih.gov/pubmed/33401457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10010057
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